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Lipid nanoparticles (LNPs) offer significant advantages as a delivery system for a nucleic-acids therapeutics. In addition to functional advantages, such as biocompatibility, biodegradability and high entrapment efficency, LNPs can be manufactured rapidly, reproducibly, and with high scalability. At Curapath, we optimize LNP formulation during pre-clinical research and development in order to determine the optimal conditions for the encapsulation of nucleic acids.
Resources
Polymeric Nanoparticles Case Study
Development of a Highly Efficient, Biodegradable, Polymeric, Non-viral Vector (NVV) Platform for Nucleic Acid Delivery
Curapath-Knauer Application Note
Development and Optimization of LNP Formulations using the NanoScaler

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